Genetic Testing For Alzheimer’s Disease

Written By: Indus Health Plus Doctors Team

Medically Reviewed | Based on Clinical Guidelines

Last Updated : 30 Sep 2022

Genetics of Alzheimer Disease, blood test for Alzheimer’s gene, Does Alzheimer run in families?

The exact cause of Alzheimer’s disease is not known; however, the involvement of genes is well known. With advancements in research and technology, research has shown how specific genes are likely to affect you to get Alzheimer’s disease.  

What is Alzheimer’s disease? 

Let’s understand the genetics of Alzheimer disease. Genes contribute significantly to the development of different types of dementia, though the level of this role differs with the dementia type. However several factors need to be considered, an individual with a sibling or parent with dementia like Alzheimer’s disease is at increased risk of developing the same condition themselves. 

A mutation (change) in one of a small number of genes can lead to frontotemporal dementia or rarer, inherited forms of Alzheimer’s disease.  

How does Alzheimer’s cause? 

Does Alzheimer run in families? Anyone who has a family history of Alzheimer’s disease might sometimes have worries about “senior slip-ups” or heading towards the same path with age. However, family history is unnecessary for a person to develop Alzheimer’s. Though research shows the increased risks with family history, genetics (hereditary factors), as well as environmental factors or both, can contribute a role. 

Genetic Testing for Alzheimer’s Disease 

Thanks to technology and genetic testing. It provides us with a ray of hope and makes it possible to get clues about your future health risks. Just by swabbing your cheek or collecting a saliva sample, the health care experts can get insights about future health risks or increase your chances of getting the right treatment at the right time.  

A blood test for Alzheimer’s gene can tell which APOE gene you have; however, the outcomes can’t foretell whether you are likely to get Alzheimer’s. These tests are mostly used by experts for the purpose of research. In some families, Alzheimer’s disease strikes early and fairly often. It is known as early-onset familial Alzheimer’s disease. Experts do not usually recommend genetic testing for late-onset Alzheimer’s as the outcomes can be unclear and have effects like emotional distress.  

If you or your near dear one has a family history or symptoms, your healthcare expert may ask to test for early-onset Alzheimer’s. Experts can usually diagnose Alzheimer’s without any genetic test. You can take a genetic test for Alzheimer’s disease to check the likelihood of the disease. However, it is essential to understand the emotional aspects associated with the results. Also, seeking the services of a certified genetic counselor before and after deciding to undergo testing is recommended. Remember, genetic testing is only an option for families that have young-onset familial Alzheimer’s disease.  

It is true that Alzheimer’s cannot be prevented. However, with modifications in the diet and lifestyle along with regular comprehensive health checkups, one can keep a check on the advanced stages of the disease.   

Before making a decision and consenting to genetic assessment or testing, consider the ethical, psychological, social, and legal effects of genetic testing. 

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