Age and gender are the most important non-modifiable factors that influence the risk of COVID-19 associated complications. Apart from that, existing health conditions, lifestyle factors and GENETICS affects your overall risk for COVID-19 infection. As the COVID-19 pandemic is new, the knowledge regarding the role of host genetics is still evolving. However, available data indicate that genetic makeup of an individual indeed affect the susceptibility (risk) and severity of COVID-19 infection.
Your genes can determine how prone you are for infectious diseases such as COVID-19, and also influences your chances to develop complications from these infections. Some individuals who get infected remains asymptomatic, some develop mild symptoms while a few experience severe symptoms requiring hospitalization.
This inter-individual variation may be caused due to polymorphisms in various genes. This is because your GENES controls the immune system also, a system in your body to fight against infections. The immune system is constantly on alert watching your body if it is being attacked by bacteria, virus, etc. Under normal circumstances, the immune system mounts a response against these disease causing pathogens and protects you. Presence of certain genetic variants can however influence this response and make you more susceptible to certain bacterial and viral infections including COVID-19.
Genes encode for proteins (Hormones and enzymes) that play an important role in the metabolism of various macronutrients and micronutrients (vitamins and minerals). Certain micronutrients like vitamin C, vitamin D, zinc etc. are involved in regulation of the immune responses and hence it is important to maintain normal levels of these vitamins and minerals to achieve optimal immunity against various infections like COVID-19. Presence of genetic variants in some genes can interfere with the levels and activity of these and thus influence the immune system of an individual.
COVIDNAwise Genetic report will help you understand your genetic risk for COVID-19 infection and severity. This report is based on analysis of SNPs in genes that are shown to influence your immune health; susceptibility for various complications associated with COVID-19 infection and provides you with suggestions to prepare you for COVID-19.
Preparing for COVID-19 includes taking measures for maintaining optimal health to prevent infection and to be aware about what to do when you do get an infection.
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Genetic susceptibility for COVID-19 and genetic risk of various parameters associated with COVID-19 infection are reported as 18 parameters in 3 categories as described below
Susceptibility and Severity of COVID-19
Nutrition and COVID-19
Co-morbidities of COVID-19
Disclaimer : COVIDNAwise is not a diagnostic report and is designed for informational purposes only. COVID-19 is a result of complex interaction between genetic factors and environmental or lifestyle factors. Also, as COVID-19 pandemic is ongoing, the science is still at an early stage and understanding of the link between genetics and COVID-19 is still evolving. Although, there is still a lot to understand yet, there exist studies that show association between different genetic polymorphisms and risk of various COVID-19 related parameters. Based on this latest available knowledge, Indus Health Plus came up with this COVIDNAwise test. The aim of this report is to provide meaningful insights and easy to implement lifestyle recommendations that will help you to take educated decisions to prevent and manage COVID-19 and achieve your health and wellness goals. Please note that, a low risk given in the report implies low genetic risk and does not guarantee that the individual will not contract the infection, even upon exposure to virus. Similarly, a high genetic risk does not mean that the individual will certainly get the infection, even if he follows all the safety measures. It is important to understand that while your genetic risk can be useful in guiding prevention and management of COVID-19, exposure to SARS-Cov-2 virus is still the most critical factor that influences your chances of acquiring COVID-19 infection. You are therefore advised to follow all the safety measures and guidelines outlined by WHO, Government of India and your local government bodies for COVID-19.