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Liver Function Tests

Liver function tests are a group of tests conducted in blood that help in diagnosing liver disorders and to detect inflammation and damage to the liver. LFT also check how well the liver is functioning. The tests measure the levels of certain enzymes and proteins in the blood.

Liver Function Tests

Australia Antigen Test for Hepatitis B

Also known as HBsAg and Hepatitis B Surface Antigen, Australia antigen is Hepatitis B surface antigen. A positive Australia antigen test report means that the person may be suffering from hepatitis B. This may be acute hepatitis, chronic hepatitis or in carrier state. This test is done in a blood sample.

Liver function tests are done if:

  • You are on a long term regime of medication that can harm the liver
  • You have any suspected liver disease
  • You have symptoms of bile or liver disease ( such as abdominal pain, nausea and vomiting, or yellowish discoloration of skin)
  • You drink alcohol regularly and excessively

Tests for liver enzymes

ALT and AST:

These enzymes, formerly known as SGOT and SGPT, are normally found in liver cells that leak out of cells and mixes in blood when liver cells gets injured. The ALT is a more specific indicator of liver inflammation as AST can also be found in other organs like heart and skeletal muscles. Due to injury to the liver, as in cases of viral hepatitis, the level of the ALT and AST may be used as a general indicator of the degree of liver damage or inflammation.

Alkaline phosphatise:

The alkaline phosphatise is a commonly used test to detect obstruction in the biliary system (bile vessels). Elevation of this enzyme may be found in gallstone disease, excessive alcohol abuse and drug-induced hepatitis. It can also be found in primary biliary cirrhosis (PBC) or biliary tumours.

Other tests:


Bilirubin is the primary bile pigment which, when elevated causes the yellow discoloration of the skin, commonly known as jaundice and is a byproduct of the normal breakdown of red blood cells in the body. Bilirubin can be elevated in many forms of liver or biliary diseases.


It is a major protein which is formed by the liver. Although there could be several factors which can affect the level of albumin in the blood but chronic liver diseases causes a dip in the amount of albumin produced, and therefore the level of albumin in the blood gets reduced and shows up in the albumin test.

GGT and LD

Gamma-glutamyltransferase is an enzyme found in the blood. Abnormally high levels may indicate liver or bile duct damage.

L-lactate dehydrogenase is also an enzyme found in the liver and its elevated levels may indicate liver damage.

A regular preventive health checkup will keep you updated with the status of your liver and its functioning.

To live healthy & happy, one must keep a check on the body’s functioning by going for regular health checkups. This helps in assessing risk factors and diagnosing diseases at an early stage, which will result in effective treatment and better management of the condition.

Know your complete health status by comprehensive checkup packages designed and facilitated by Indus Health Plus, the preventive checkup specialist.

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